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Mark Myers

2022 Research Grants


Research is the key to ensuring children with cancer have the opportunity to thrive long beyond diagnosis. CURE’s research priorities are two-fold. First, we prioritize research that will lead to more effective treatments for children within two to three years. We also prioritize research aimed at solving recurrent and hard-to-treat cancers for which no effective treatment exists. Precision medicine, gene-based therapy, continues to be our highest priority, as we believe this approach to treatment shows extraordinary promise.

In response to CURE’s request for proposals, we received dozens of studies seeking funding. Expert oncologists and academic researchers reviewed and scored each proposal using the same process employed by the National Institutes of Health. Their scores and critiques guided CURE’s board, ensuring we invest funds in the most strategic and prudent fashion.

We are proud to share that our 2022 research grants are focused almost entirely on helping children facing the toughest diagnoses – high-grade brain tumors, aggressive leukemias and solid tumors, and metastatic disease. These 18 grants awarded to top scientists at leading pediatric cancer research institutions across the nation total more than $4.7 million, CURE’s highest disbursement in a single grant cycle in our 47 year history.

“We are so pleased and proud that CURE is providing such a high level of support to very promising research this year,” said Kristin Connor, CEO of CURE Childhood Cancer. “We are urgently focused on getting new treatments to those children with high-risk, difficult-to-treat cancers that currently lack effective treatments. Virtually all our grants this year are aimed at doing that, which gives me so much hope for these children.”

The grant includes funding for these difficult to treat cancers:

  • 5 High-risk blood cancer studies (3 AML, 2 B-cell ALL)
  • 7 High-grade brain tumor studies (3 DIPG, 1 high grade glioma, 3 medulloblastoma)
  • 2 High-risk solid tumor studies (neuroblastoma and Ewing sarcoma)

In an effort to ensure the best and brightest young minds are trained to care for children with cancer and advance research, we also proudly announce our funding of the fellowship training of three pediatric oncology fellows at Emory University’s School of Medicine: Dr. Frank Chien, Dr. Robert Lisac (Sam Robb Fellow), and Dr. Sanyu Janardan (Connolly Family Fellow).

Our 2022 Pediatric Cancer Research Initiative includes the following studies:

Aflac Cancer and Blood Disorders Center at Children’s Healthcare of Atlanta

Aflac Precision Medicine Program

Robert Castellino, MD
Combined molecular targeting to enhance therapy for group 3 medulloblastoma

Tobey MacDonald, MD 
Clinical investigation of cluster-wells in pediatric brain tumors

Christopher Porter, MD
Targeting mechanisms of T cell suppression mediated by Siglec15

Sunil Sudhir Raikar, MD 
Optimizing gamma delta T-cell immunotherapy for acute myeloid leukemia

Renee Read, PhD   
Human organoid models of pediatric high-grade gliomas

Muxiang Zhou, MD
Feasibility study of VERU-111 for precision treatment of pediatric AML

Beckman Research Institute of the City of Hope

Ling Li , PhD
Targeting PRMT1 elicits anti-tumor immunity in childhood leukemia

Qiang Lu, PhD
Developing inhibitors of mitotic kinesin KIF20A for brain tumor treatment

Children’s Hospital of Philadelphia

Michael Chorny, PhD 
Macromolecular prodrug-based therapy for indolent neuroblastoma

Timothy Olson, MD, PhD
Targeting niche inflammation and MSC cell fate in monosomy 7 predisposition

Vinodh Pillai, MD, PhD 
Assessment of bone marrow to predict response to CAR T-cell therapy

Indiana University

Jignesh Tailor, PhD
Discovery of synthetic lethal targets in MYCN neuroepithelial stem cells

Seattle Children’s Hospital

Elizabeth Lawlor, MD, PhD 
Optimizing safety and efficacy of anthracyclines in Ewing sarcoma

University Hospitals Rainbow Babies & Children’s Hospital

John Letterio, MD 
Development of a CNS-penetrant synthetic oleanane triterpenoid for DIPG

University of Texas Health Science Center at San Antonio

Raushan Kurmasheva, PhD 
PEGylated talazoparib for pediatric malignant rhabdoid tumor therapy

Virginia Institute of Technology

Jia-Ray Yu, PhD 
Pharmacological screening of a new class of NSD1 inhibitor

Washington University in St. Louis

Jason Weber, PhD  
Development of p14ARF-based therapies to treat CDKN2A-deficient pediatric cancers

Claire’s Crew

In September 2020, Claire woke up one day complaining of leg pain. Her mother, Kathleen, noticed a sizable bump on her upper thigh and took her to their pediatrician, who determined it to be an infection. After ten days of antibiotics did nothing to reduce the size of the bump, Claire was taken for an ultrasound.

“I knew right away that something wasn’t right,” said Kathleen. “After the scan, the ultrasound technician immediately went out of the room and talked to the radiologist.”

A follow-up CT scan revealed that Kathleen was right. Claire was scheduled for immediate surgery, after which they would learn that the bump was cancer. The makeup of the tumor was consistent with b-cell lymphoblastic leukemia/lymphoma. Fortunately, her bone marrow came back clean.

“Claire was lucky because we caught it very early,” shared Kathleen. “After testing on the lymph nodes, it showed her cancer to be lymphoma and not leukemia. But because it is very rare for a four-year-old child to get lymphoma and her disease is presenting like leukemia, we are doing the standard treatment for leukemia.”

The good news is that the change in diagnosis meant that Claire’s cancer was considered low risk.

Claire has responded very well to the chemotherapy. She has little nausea and is able to continue doing the things she loves – riding horses, dancing, and playing with her little brother. She also has been able to go to school, which makes her very happy. Claire should be done with her treatment in November.

Claire’s family has received tremendous support from their Dunwoody community. During September’s Childhood Cancer Awareness Month, Claire’s Crew held a walk to raise money for childhood cancer research. It was a very festive atmosphere with popsicles, bubbles, and lots of fun activities for the kids. The afternoon also raised $10,000 to fight childhood cancer!

“I can’t help her with the medical stuff,” said Kathleen. “But I have to do something. It is so important that we fund research that will lead to a cure for these kids. Claire was one of the lucky ones. When we are at the hospital, I look around and see the other kids, and my heart breaks for them.”

Though Claire will be done with her fight later this year, Claire’s Crew isn’t finished fighting for other kids with cancer. Kathleen and her family are planning a big event for 2023 and hope to raise even more than before.

We are thankful that Claire is doing so well. We are also grateful to join Claire’s Crew to fund research that will lead to better cures for kids with cancer.

Shelby’s Mission

When Shelby Howerton was three years old, she dressed as her favorite princess for Halloween. While Cinderella didn’t stay out until the stroke of midnight, she did come home with very sore legs. Her parents assumed she had shin splints because of all the walking she did to collect candy. But her legs continued to hurt long after Halloween. When she developed a persistent fever, her mother took her to the emergency room, where she was diagnosed with leukemia.

At the time, the standard treatment for leukemia lasted three years. Shelby’s doctors decided she was a good fit for a clinical trial that was shorter but more intense. She was supposed to finish in two years. But she contracted parvovirus when she was immunocompromised, which extended her treatment by six months. The trial worked, and she has been cancer-free ever since.

Shelby and her twin brother, Caleb

Today Shelby is healthy and happy. She can run a mile in under six minutes, and later this month, she will graduate from Milton High School. But she never forgot the days she fought cancer. In fact, that experience has shaped her in many ways.

When she was in middle school, her sister, Faith, started a CURE Club at Milton High School. She also became very active in the Health Occupational Students of America (HOSA) club. Faith was instrumental in the club’s push to collect toys and toiletry items for children currently battling cancer. When Faith graduated, Shelby stepped right in and continued the effort.

“We start collecting after winter break and continue until the semester ends,” Shelby explained. “Then I bring everything to CURE on Christmas Eve. Raising awareness for childhood cancer and bringing in donations is the absolute least I can do to help children with cancer.”

Shelby has plans to do much more. After graduation, she will begin her studies at Georgia Tech in the fall, majoring in neuroscience. Her goal is to become a pediatric oncologist, just like the doctors who treated her.

“Whenever I thought about a career path, my head jumped immediately to being in the hospital,” Shelby said. “There is a difference between telling your story and doing something about it. I feel like I need to do something to help kids.”

Shelby has already done so much. She has already handed off the leadership of the CURE Club at Milton High School to a new officer. Not surprisingly, she made sure to get a commitment that the toy donations will continue after she is gone.

Congratulations, Shelby. We appreciate how much you’ve done to encourage children with cancer, and we look forward to seeing all you do to care for them in the future.

Carrying Hope

Trenton Kindred will carry an extra bit of hope when he walks across the graduation stage in his scarlet cap and gown. Not only hope for his future that was once in doubt, but he also carries a special hope for others that he and his family have nurtured since 2006.

When Trenton was only one year old, he was diagnosed with stage four neuroblastoma. His parents, Greg and Ginger, had to watch as their baby began a very harsh treatment and all its horrible side effects. They were told he had a 20% chance of survival and a 70% chance of relapse. Before reaching his 25th month, Trenton endured five rounds of intense chemo, two bone marrow transplants, 21 days of being put to sleep during radiation treatments, several surgeries, 27 port line infections, and six months of oral chemo.

Through it all, Trenton fought back. His determination and love of life helped him get through these rigorous challenges. In 2006, Trenton was declared cancer-free.

“Trenton’s experience has shown us the huge need for less-toxic cancer treatments specifically tailored to kids and their growing bodies,” Ginger said. “Our family hopes that in the future, no other family will ever hear the heart-sinking words ‘Your child has cancer.’ But if that does happen, there will be hope – a hope of a cure and less toxic treatments tailored to kids that will allow them to be kids that grow into healthy adults.”

Not ones to sit idly by and let others do the work, the Kindred family started the Trenton W. Kindred Research Fund, a named fund at CURE. The purpose of the fund is to support childhood cancer research. The Kindreds and their supporters are committed to advancing better treatment for neuroblastoma and, ultimately, to find a cure for this aggressive disease. To date, the fund has raised $303,465 to fight childhood cancer! That is a lot of hope that Trenton and his family have provided to other children in the fight.

And Trenton? He’s doing great these days. After graduating with honors, he will head to Oglethorpe University in the fall, where he will study Business Administration and Economics. He’s not 100% sure where that will lead but is hoping to further his education in law school as a corporate or commercial real estate lawyer.

“He continues to amaze us with his infectious humor, shyness, and love for life,” said Ginger. “He’s an old soul, and he is fearless. But he is also reserved and has a soft soul that we think comes from staring into the darkest of places at such a young age. He is truly a miracle, and our family lives each day not taking anything for granted.”

Nicholas’s Bright Future

Later this month, Nicholas Childers will walk with his fellow seniors as they graduate from St. Andrews School. By all accounts, his future certainly looks bright. Most people who see him in his blue cap and gown will never know that there was a time when his future was in doubt. But even at his young age, Nicholas has fought a battle that most can’t fathom.

In 2015, ten-year-old Nicholas began experiencing persistent nausea and fever. His parents were told it was a virus. But after it wouldn’t go away after two months, they knew it was something more. On April 3, blood work revealed that Nicholas had B-cell high-risk acute lymphoblastic leukemia.

“Nicholas responded well to treatment in the beginning,” shared his mother, Cheryl. “But things went downhill fast. The nausea was relentless. He had pancreatitis from one chemo and had to have his gallbladder removed. Then he had an anaphylactic reaction to another drug. It was awful.”

Today’s treatment for leukemia lasts approximately three years. Nicholas reached remission in the first month. But a year later, the side effects were still affecting him, and the anti-nausea medications were not helping. So his doctors decided to stop his medications for a week to let his body recoup. His next spinal tap revealed that Nicholas had relapsed.

“At this point, Nicholas needed a bone marrow transplant,” Cheryl said. “We had everyone tested, and no one was a match. Fortunately, a perfect match was found in a woman in England. She went through the donation procedure, and Nicholas had the transplant in April 2017.”

While the transplant was difficult for him, he was declared cancer-free the following month and finished treatment in December. He hasn’t looked back.

Nicholas loves animals and talked about going to veterinary school after college. But he shadowed a friend in a veterinary clinic and decided that line of work wasn’t for him.

“After that experience, he was able to shadow our dentist and has really enjoyed it,” Cheryl said. “So he will be studying biomedical sciences at the school of Health Professions at The University of Alabama at Birmingham and plans on becoming a dentist! He’s very excited about it.”

At CURE, we love seeing kids persevere through their struggles and have the opportunity to live out their dreams. We will be cheering Nicholas on as he graduates and moves on to college!





What it Means to be a Quiet Hero

On May 14, we will gather in person for A Tribute to Our Quiet Heroes. This special luncheon honors the mothers of children diagnosed with cancer, who guide their families through an unimaginable journey. The last two years have been virtual events, and many mothers whose children have been diagnosed during that time have no idea what to expect. So we sat down with Ramona King, whose son Ezra, was diagnosed with a brain tumor in 2018.

CURE: What is it like to be a mother walking through childhood cancer?

When Ezra was first diagnosed as a baby, I was terrified, mad, and alone. I felt like the only mother in the world having to deal with something so horrific. And in my own little world, I was. However, I soon found out that I am the farthest from being alone. There is a community of amazing mothers who are strong fighters for their children battling these diseases. I still struggle. I feel resentful at times for this being our story. I want so differently for my beautiful little boy. I have to fight so hard for his care, research things I never even dreamed of, and hold his body through things that children should never have to go through. It is traumatizing. However, I am a better person and a better mother for it. My perspectives on life and what is most important have shifted in the best way.

CURE: What was your first impression when you got the invitation to A Tribute to Our Quiet Heroes?

My first impression when I heard about it was to not go. That sounds weird but I felt nervous. I didn’t know what to expect. I felt so alone, and I thought by going and being around that many people, I’d feel even more alone. My husband urged me to go. I was timid when I parked and walked in. I felt overwhelmed. As soon as I put my name tag on, I felt like I was somebody. Not just someone who was hurting inside secretly, but like someone who everyone else with a nametag could relate to. I quickly made friends and saw other moms I had seen in the hospital hallways.

CURE: Did you enjoy the event?

I went to the Quiet Heroes event for the first time in 2018, just weeks after my baby began chemotherapy. I felt overwhelmed at first, but I quickly realized that I was in a room full of mothers who knew just exactly all that I had been through and felt during those horrific months following diagnosis. I wasn’t alone in my heartbreak for the first time. There were hugs, smiles, tears and “I’ve been there’s.” It was incredible. It felt nice to have an event just for me.

CURE: What was your biggest take-away?

It was like I could finally relate to someone face to face. For months in my community, I was the person everyone couldn’t look at, the person they pitied. I was the mother living everyone’s worst nightmare. At Quiet Heroes, I was just a friend. I could look into other moms’ faces and understand what they had been through, too. There were moms fresh in the fight and those that had decades of experience being in these shoes. It was so nice not to be the sad person in the room. We were all strong moms who had all walked similar paths.

CURE: Are you excited about Quiet Heroes being in person again?

I cannot wait to attend this year! I get to see friends that I haven’t seen in a while. I always am so proud to see my son’s sweet face on the screen. It’s a mix of fellowship, friendship, hugs, tears, and feeling so proud of our children who have been through so much.

CURE: What would you tell a mom whose child has recently been diagnosed with cancer?

You feel alone. You are the only person you know in your community who is hurting like this. But I want you to know that you aren’t alone. There are moms who have been where you are, who have had their hearts broken, have had to hold their child through the worst. We want to meet you because you make us feel not alone, too. There are so many of us out here making these tough decisions.

CURE: What would you tell a mom who might be hesitant to go to Quiet Heroes?

Just go. Just try it. You will love it! Just stand tall and be brave for a few minutes and get yourself in the door. Once you find a seat, you will realize you are a part of a friendly, fun, and amazing community of warrior moms.


You are invited to join us as we honor the mothers of children with cancer at A Tribute to Our Quiet Heroes. This luncheon features inspiring speakers, a special musical performance, and an over-the-top silent auction and raffle. It is also a day to raise money to fund critical research aimed at solving cancers that affect children.

Won’t you join us?

Get Tickets

Advancing Science Together

As you read this, CURE’s Peer Review Committee is evaluating 44 research proposals from scientists at 27 institutions who are seeking funding. Based on their feedback, we will select the life-saving research that we fund in our next award, and you can have a direct impact on the process.

These proposals have the potential to significantly improve treatments for pediatric cancers where current options are not adequate and, if funded, to be in clinical testing or treatment phases within 2-3 years.

The committee is reviewing cutting-edge research and will score proposals the researchers hope will lead to better treatments for cancers that affect children. These proposals include new methods to fight the most common cancers like leukemia and lymphoma. They also seek to advance science that will impact children diagnosed with the hardest to treat brain tumors, sarcomas, and metastatic disease.

These proposals have come in from leading research institutions across the country.

Each submission is being reviewed by two committee members who have specific knowledge and interest in the cancer type of the proposal. In May, we will host a meeting during which every submission will be discussed by the entire committee. Members will have the opportunity to ask questions and vote to accept or change the overall score. These final scores will be ranked and presented to CURE’s Board of Directors on June 21, and final funding decisions will be made.

This is where you come in. Before the funding decisions are made in June, you can increase the amount of funding available for these projects by renewing your gift by May 31. Additionally, because of a $100,000 matching gift from a generous donor, your impact could be doubled. This is a chance for you to make a direct impact on the way we treat childhood cancer.

The Hard Work of CURE Crew

“As a former teacher, I love working with students,” said CURE Vice President, Mandy Garola. “In 2020 we decided to form a teen council to give students an opportunity to get involved in the work that CURE does in South Georgia.”

The purpose of CURE Crew Teen Council is to offer high school juniors and seniors in the Savannah and South Georgia area the opportunity to support CURE through fundraising, volunteering, advocacy, and awareness of pediatric cancer. The 40 students on this year’s CURE Crew worked hard over the past twelve months. Here is a list of their accomplishments:

  • Sold 418 gold mailbox bows/flags
  • Secured 5 new business partners during childhood cancer awareness month
  • Planned and executed 6 gold-out athletic games and events in September
  • Planned and executed 3 dress down days benefiting CURE
  • Volunteered at 6 annual CURE events
  • Delivered Holiday Angel gifts to 12 local families that would have otherwise struggled to provide gifts for their children this year
  • Helped execute our 1st Holiday Family Drive-In Movie dressed as Who’s from Whoville
  • Secured 4 event business sponsorships and over a dozen auction items
  • Sold dozens of raffle tickets
  • Poured many glasses of tea and water at our Catie’s Gathering events in Savannah and Effingham
  • Established CURE Clubs at 2 local high schools
  • Worked with school groups to collect donations and assemble bags for patients
  • In addition they’ve created birthday and end of chemo posters, donated Halloween door decorations, Valentine’s Candy, and made valentines day cards for patients

“After our 2020 Patient Family Drive-Thru Holiday Party was fully executed with the help of CURE Crew students as volunteers, I officially proclaimed that students are better volunteers than adults,” shared Mandy. “I’m not sure if it’s that I was more comfortable telling them what to do or if they were more used to taking orders, but they were amazing and have been ever since.”

Here is a list of the 2021-2022 CURE Crew:

Kalin Bostic
Banks Bradley
Christian Brown
Clara Coppock
Annalin Crawford
Gracie Daters
Thomas Davidson
Colin Dragon
Madeline Drew
Kinsey English

Katherine Ezelle
Mya Felser
Cecilia Frey
John Thomas Gard
Cade Garola
Claire Hayes
Landyn Hildebrandt
Layla Hill
Haley Hiltzheimer
Grace Mahfet

Rylee Mills
Grace Nilson
Chloe Paulick
Zachary PInyan
Anslee Poppell
Jaslyn Price
Cheyenne Ryan
Reese Ritchie
Nicole Sakuma
Colson Slaughter

Harden Smallwood
Matthew Smith
William Smith
Joseph Stoever
Charlton Strong
Bryce Thomas
Gianni Valoze
Andrew Wadley
Jordan Washington
Olivia Wells

“It’s been our pleasure to work with these students,” said Mandy. “I hope they’ve learned some things about childhood cancer, compassion, fundraising, and serving others from this experience.”

CURE Crew is accepting applications for the 2022-23 school year through May 15th.  Rising juniors and seniors may apply by clicking the button below.

A Record-Breaking Night

Catie’s Gathering started after Jenny Wilkins lost her four-year-old daughter, Catie, to medulloblastoma. One day, Jenny’s friend, Tonya, turned to her and said out of the blue, “Let’s have a dinner and give the proceeds to CURE.”

Thanks to the overwhelming support of her Effingham community, the first Catie’s Gathering has grown into events in five cities across south Georgia and has raised more than $2.8 million. The event helps fund patient and family programs as well as CURE’s Precision Medicine Program, which focuses on individualized treatments based on each child’s genetic makeup.

This year’s event was one for the record books! Catie’s Gathering Effingham, presented by Carlson & Co., was back as an in-person event at the Clarence Morgan Gym in Springfield. Thanks to the tremendous way the community supports this event – it was an amazing night. In addition to sponsoring, Carlson & Co. helped with planning and logistics for the event and supplied tables, chairs, and the evening’s décor. Long-time CURE partners Kaufman-Heinz handled all audio-visual needs for the event.

For the first time in Effingham, there was a VIP tent for sponsors and special guests to kick the night off. Delicious appetizers and a beautiful charcuterie board, both provided by Southern Kafe on 17, and music from Lyn Avenue, set the tone for a fun time in the VIP tent. Meanwhile, guests in the main venue were checking out the tables, beautifully decorated by our hostesses, and perusing auction items while enjoying music from Tell Scarlett.

Attendees were then treated to a delicious meal from Simply Southern Catering, followed by an incredible live auction (complete with a puppy, a trip, and more being auctioned off), door prizes, and two exciting raffle drawings. Former board president for CURE Childhood Cancer, Janet Street, shared her family’s journey through childhood cancer with Cam, a young man gone far too young. While Cam’s story has a tragic ending, Janet shared about his joy despite difficulties and how her family has found a way to move forward after their incredible loss.

The event raised more than any other Catie’s Gathering event to date – an astounding $340,000!

“Effingham County was Catie’s home,” said Jenny. “Our neighbors stood by my family from day one, and the generosity of this community continues to amaze me. Every year, Tre and I are blown away at the support they give children with cancer through this event.”

Thank you, Effingham County, for your generous spirit and for coming out to enjoy a great night!

The Long Journey from Idea to Bedside

Dr. Michael Jensen of Seattle Children’s Hospital is one of the leading authorities on CAR T-cell therapy. He has been working on CAR T-cell therapy for many years, and his work is proving to be very beneficial for pediatric cancer patients. This type of therapy provides hope that someday children can receive far less-toxic medicines that lead to a cure.

Dr. Jensen started his career in the late 1990s at City of Hope National Medical Center in Los Angeles, where his research looked at the technology to take immune cells from a cancer patient and genetically modify them to recognize and attack cancer cells. This is something the patient’s natural immune system can’t do. His research was groundbreaking at that time, and his lab had to build everything from scratch.

“This was similar to creating the Apollo rocket and trying to land on the moon,” Dr. Jensen said. “We had to invent and create every step of the process and make sure the quality was sufficient. Once the first cells were infused, it was literally like landing on the moon and hoping that everything went right.”

It took over a decade of small trials to work out each and every kink, and obtaining funding for something so revolutionary was challenging. One source of consistent funding came from Lauren’s Run. From the beginning, Lauren’s parents were looking for groundbreaking research that would help children with cancer. After learning of Dr. Jensen’s research, they decided that it was exactly what they were looking for and made sure proceeds from the race supported his work.

His breakthrough came in 2014, when doctors using the patient’s own immune system through CAR T-cell therapy started seeing dramatic remissions in children with leukemia who were otherwise out of options.

“Without a functioning immune system, cancer would be much more common,” explained Dr. Jensen. “Think of cancer cells as a semi-truck on a freeway down a mountainside with the brakes broken, and the gas pedal stuck on full. On the way down, the cells acquire genetic programs and mutations and become uncontrolled. The human immune system is challenged because this isn’t a virus that came from outside the body. It doesn’t help that the cancer cells create deflector screens to fool the immune system into peaceful coexistence when we would like for the immune system to attack.”

CAR T-cell therapy takes the T-cells out of the body and supercharges them. The supercharged cells are then put back into the body as a surprise attack on the cancer cells, and the deflectors are not always effective in turning off the immune response. Ideally, within a week or two, the patient goes into remission. The cells then continue to move to all parts of the body, hunting and eliminating any remaining cancer cells. Over 90% of leukemia patients whose initial treatment didn’t work go into remission when given CAR T-cell therapy!

Leukemia was the first target, but the goal is to get CAR T-cell therapy to work against other childhood cancers. CAR T-cell therapy represents a major step toward a safer cure for children. It started as an idea in the mind of brilliant researchers years ago and is now a frontline treatment for many children. But it didn’t happen overnight. It was a long process, and Lauren’s Run was with them every step of the way.